Iduronate 2 sulfatase antibody Mouse Monoclonal from Proteintech validated in Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF),Enzyme-linked Immunosorbent Assay (ELISA) applications. This antibody reacts with human, mouse, rat , pig samples. Cat.No. 66112-1-Ig.
The report on Global Iduronate 2 Sulfatase Market offers in-depth analysis on market trends, drivers, restraints, opportunities etc. Along with qualitative information, this report include the quantitative analysis of various segments in terms of market share, growth, opportunity analysis, market value, etc. for the forecast years.
Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists. Iduronate-2-sulfatase (IDS) is a lysosomal sulfatase that prevents the accumulation within the brain of glycosoaminoglycans. However, IDS does not cross the blood−brain barrier (BBB). To enable BBB transport, human IDS, minus its signal peptide, was fused to the carboxyl terminus of the heavy chain of a chimeric monoclonal antibody (mAb) to the human insulin receptor (HIR). The HIRMAb Iduronate 2 sulfatase antibody Mouse Monoclonal from Proteintech validated in Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF),Enzyme-linked Immunosorbent Assay (ELISA) applications. This antibody reacts with human, mouse, rat , pig samples.
Enzyme levels may be normal in individuals receiving enzyme replacement therapy or who have undergone bone marrow transplant. Iduronate-2-sulfatase can also be deficient in individuals with multiple sulfatase deficiency. Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Background: Iduronate 2-Sulfatase/IDS As a member of the sulfatase family, IDS is required for the lysosomal degradation of the glycosaminoglycans (GAG) heparan sulfate and dermatan sulfate (2, 3). It hydrolyzes the 2-sulfate group of the L-iduronate 2-sulfate units of the GAG. Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Iduronate-2-Sulfatase (IDS) in samples from serum, plasma, tissue homogenates and other biological fluids with no significant corss-reactivity with analogues from other species.
IDS = Iduronate 2-Sulfatase Letar du efter allmän definition av IDS? IDS betyder Iduronate 2-Sulfatase. Vi är stolta över att lista förkortningen av IDS i den största databasen av förkortningar och akronymer. Följande bild visar en av definitionerna för IDS på engelska: Iduronate 2-Sulfatase.
Storage. Store it at +4 ºC for short term.
motif-containing protein 2 OS=Crassostrea gigas GN=CGI_10001579 PE=4 Iduronate 2-sulfatase OS=Crassostrea gigas GN=CGI_10000812 PE=4 SV=1
Format: 96-well plate with removable strips. Compatible samples: cell culture supernates, cell Iduronate Sulfatase. Iduronatsulfatas.
Demonstration of deficient iduronate-2-sulfatase enzyme activity is considered the gold standard to confirm a diagnosis of Mucopolysaccharidosis II (MPS II), Hunter Syndrome. In addition, it can be used to clarify molecular findings in the IDS gene and to follow up abnormal newborn screening results. Turnaround Time . 14 days.
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Mucopolysaccharidosis type III: MedlinePlus Genetics image. Mucopolysaccharidosis type II Osteoimmunology in mucopolysaccharidoses type I, II, VI and Die Heparitinsulfat-Mucopolysaccharidose (Sanfilippo PDF) BMN 250, a fusion of lysosomal Iduronate 2-sulfatase (IDS) is a sulfatase enzyme associated with Hunter syndrome. Iduronate-2-sulfatase is an exo -sulfatase that hydrolyzes the C2-sulfate ester bond from nonreducing terminal α-L-iduronic acid residues in HS (Fig.
Invitrogen Anti-Iduronate 2 Sulfatase Monoclonal (OTI4G2), Catalog # MA5-25866. Tested in Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin) (IHC (P)) and Flow Cytometry (Flow) applications. This antibody reacts with Canine, Human, Mouse, Non-human primate, Rat samples.
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IDS. Gene description i. Full gene name according to HGNC. Iduronate 2- sulfatase. Protein class i. Assigned HPA protein class(es) for the encoded protein (s).
Liquid or lyophilized powder. Enzyme Commission Number. EC 3.1.6.13. CAS No. 50936-59-9.
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Cite This Product: Human IDS/Iduronate 2 Sulfatase ELISA Kit PicoKine™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # EK1452) ELISA Validation Each Iduronate 2-Sulfatase/IDS Antibody is fully covered by our Guarantee+, to give you complete peace of mind and the support when you need it. Our Iduronate 2-Sulfatase/IDS Antibodies can be used in a variety of model species: Canine, Human, Monkey, Mouse, Rat. Anti-Iduronate 2 sulfatase/SIDS antibody (ab85701) at 0.1 µg/ml + Human Liver lysate at 35 µg Predicted band size: 62 kDa Observed band size: 62 kDa. Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Iduronate 2 sulfatase/SIDS antibody (ab85701) Demonstration of deficient iduronate-2-sulfatase enzyme activity is considered the gold standard to confirm a diagnosis of Mucopolysaccharidosis II (MPS II), Hunter Syndrome. In addition, it can be used to clarify molecular findings in the IDS gene and to follow up abnormal newborn screening results. Turnaround Time . 14 days.
Sangamo Therapeutics (SGMO) Updates On MPS II (SB-913) and . Early Results of First In Vivo Sangamo: Count Down To MPS II Readout - Marty Chilberg .
The symptoms of Hunter syndrome are comparable to those of MPS I. Abstract Hunter syndrome is a rare but devastating childhood disease caused by mutations in the IDS gene encoding iduronate-2-sulfatase, a crucial enzyme in the lysosomal degradation pathway of The full iduronate-2-sulfatase sequence contains seven possible N-glycosylation sites, but the number used in the 42-kDa polypeptide is not known. MPS II, resulting from a deficiency of iduronate-2-sulfatase, is the only x-linked MPS, with most mutations being restricted to individual families (75–77). The presence of a pseudodeficiency allele may cause reduced activity of iduronate-2-sulfatase in the artificial substrate used in this assay. Enzyme levels may be normal in individuals receiving enzyme replacement therapy or who have undergone bone marrow transplant. Hunter syndrome is a rare but devastating childhood disease caused by mutations in the IDS gene encoding iduronate-2-sulfatase, a crucial enzyme in the lysosomal degradation pathway of dermatan sulfate and heparan sulfate. Hunter syndrome, also known as Mucopolysaccharidosis type II (MPS II, OMIM 309900) 1, is an X-linked lysosomal storage disease caused by genetic deficiency of the enzyme iduronate-2-sulfatase (IDS Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate.
immunoglobulin G1-kappa, anti-TfR1, monoclonal antibody, fused with human iduronate-2-sulfatase, glycoform alfa, --, Engelska A progressive and complex clinical course in two family members with Identification of an alternative transcript fromthe human iduronate-2-sulfatase (IDS) Actr2, ARP2 actin-related protein 2, 8703, 131.47, 165.12, 121.77, 139.45, 1358. Actr3, ARP3 Ids, iduronate 2-sulfatase, 2315, 24.8, 25.31, 23.49, 24.53, 7023. Iduronate-2-sulfatase PAPSS2 enzym 3'-fosfoadenosin-5'-fosfosulfat, andra, png 1 2 3 4 5 textöverlägg, diagram, kreativt PPT-element, 3D-datorgrafik, Immunotag™ Iduronate 2-sulfatase ELISA Kit. Size: 1 96-well plate 0.5 - 2. Inte klassificerat sulfuric acid.